Prolapse surgery showdown: which procedure wins?
NCT ID NCT05063331
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 40 times
Summary
This study compares two common surgeries for uterine prolapse: a minimally invasive sacrocolpopexy and a vaginal hysterectomy with uterosacral ligament suspension. Researchers will track 300 women to see which surgery has fewer failures and complications from the patient's perspective. The goal is to help women and their doctors choose the best option.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Duke University
Durham, North Carolina, 27707, United States
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Mayo Clinic
Jacksonville, Florida, 32224, United States
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MetroHealth Medical Center
Cleveland, Ohio, 44109, United States
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Northwestern Medicine
Chicago, Illinois, 60611, United States
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University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
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University of Pittsburgh, UPMC Magee-Womens Hospital
Pittsburgh, Pennsylvania, 15213, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
surgery (minimally invasive sacrocolpopexy or vaginal hysterectomy with uterosacral ligament suspension)
What this could lead to
If this trial succeeds, it could help doctors and patients choose the better surgical option for treating uterine prolapse, leading to fewer failures and complications.
What could go wrong
This is an observational comparison, not a blinded trial, so results may be influenced by patient or surgeon preferences. Both surgeries have risks like pain, infection, or prolapse recurrence.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.