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Braces breakthrough? new study tests simpler glue to prevent white spots on teeth

NCT ID NCT07355322

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study compares two types of dental glue used to attach braces to teeth. One is a traditional three-step system, the other a simpler two-step system. The goal is to see which causes less damage (white spots) to tooth enamel. Thirty-four teenagers will have each type of glue used on different sides of their mouth, and the damage will be measured after braces are removed.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dental bonding system (Transbond XT or GC Ortho Connect)
What this could lead to
If successful, this could lead to a simpler, faster bonding method for braces that reduces the risk of white spots on teeth.
What could go wrong
This is a small, early-stage trial with only 34 participants, so results may not apply to everyone. The study compares two existing products, so no major breakthrough is expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 34 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2026

An estimate. Start dates often move.

Expected to finish

Apr 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

10 to 16 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient aged 10 to 16 years included, * Patient attending their first dentofacial orthopedics consultation at the Montpellier Dental Care Center, in adolescent or young adult dentition (according to Démogé classification), * Patient requiring the placement of a bimaxillary multi-bracket treatment and opting for a metallic vestibular technique. Exclusion Criteria: * Syndromic patient (all syndromes included, e.g., cleft lip) or with a severe long-term condition (ALD), * Patient previously treated with a multi-bracket orthodontic treatment using a mixed, lingual, or vestibular technique, * Any medical condition deemed incompatible with bracket placement by the investigator, * Patient with severe MIH (molar-incisor hypomineralization) and/or severe demineralization on one or more teeth (including severe amelogenesis imperfecta or dentinogenesis imperfecta), * Patient with restorations such as metal crowns, ceramic crowns, porcelain-fused-to-metal crowns, inlays, onlays, or amalgam on one or more vestibular surfaces, * Patient with oral hygiene incompatible with orthodontic treatment, * Agenesis of lateral incisors, * Subject already participating in another interventional clinical trial that could interfere with this study, * Uncontrolled psychiatric disorder, * Lack of written informed consent from a legal representative after a reflection period, * Lack of cooperation or difficulty in communication/comprehension, or refusal of participation by the minor, * Subject with a dependency or employment relationship with the sponsor or investigator, * Subject participating in another research study with an ongoing exclusion period, * Subject not affiliated with the French social security system or not a beneficiary of such a system, * Protected populations according to the French Public Health Code: Pregnant or breastfeeding women Subjects deprived of liberty (by judicial, administrative decision, or involuntary hospitalization) Subjects under guardianship or curatorship

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Conditions

The condition(s) this trial relates to.

Dental Plaque enamel caries Tooth Demineralization tooth resorption

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University Hospital Montpellier

    Montpellier, France

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