Braces breakthrough? new study tests simpler glue to prevent white spots on teeth
NCT ID NCT07355322
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study compares two types of dental glue used to attach braces to teeth. One is a traditional three-step system, the other a simpler two-step system. The goal is to see which causes less damage (white spots) to tooth enamel. Thirty-four teenagers will have each type of glue used on different sides of their mouth, and the damage will be measured after braces are removed.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- dental bonding system (Transbond XT or GC Ortho Connect)
- What this could lead to
- If successful, this could lead to a simpler, faster bonding method for braces that reduces the risk of white spots on teeth.
- What could go wrong
- This is a small, early-stage trial with only 34 participants, so results may not apply to everyone. The study compares two existing products, so no major breakthrough is expected.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 34 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2026
An estimate. Start dates often move.
- Expected to finish
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Apr 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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10 to 16 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient aged 10 to 16 years included, * Patient attending their first dentofacial orthopedics consultation at the Montpellier Dental Care Center, in adolescent or young adult dentition (according to Démogé classification), * Patient requiring the placement of a bimaxillary multi-bracket treatment and opting for a metallic vestibular technique. Exclusion Criteria: * Syndromic patient (all syndromes included, e.g., cleft lip) or with a severe long-term condition (ALD), * Patient previously treated with a multi-bracket orthodontic treatment using a mixed, lingual, or vestibular technique, * Any medical condition deemed incompatible with bracket placement by the investigator, * Patient with severe MIH (molar-incisor hypomineralization) and/or severe demineralization on one or more teeth (including severe amelogenesis imperfecta or dentinogenesis imperfecta), * Patient with restorations such as metal crowns, ceramic crowns, porcelain-fused-to-metal crowns, inlays, onlays, or amalgam on one or more vestibular surfaces, * Patient with oral hygiene incompatible with orthodontic treatment, * Agenesis of lateral incisors, * Subject already participating in another interventional clinical trial that could interfere with this study, * Uncontrolled psychiatric disorder, * Lack of written informed consent from a legal representative after a reflection period, * Lack of cooperation or difficulty in communication/comprehension, or refusal of participation by the minor, * Subject with a dependency or employment relationship with the sponsor or investigator, * Subject participating in another research study with an ongoing exclusion period, * Subject not affiliated with the French social security system or not a beneficiary of such a system, * Protected populations according to the French Public Health Code: Pregnant or breastfeeding women Subjects deprived of liberty (by judicial, administrative decision, or involuntary hospitalization) Subjects under guardianship or curatorship
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University Hospital Montpellier
Montpellier, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Braces breakthrough? varnish may stop gum overgrowth and white spots
- New cleaning method may protect braces-wearing teens from white spots and gum disease