Which ventilator weaning method works best? small study investigates
NCT ID NCT02939963
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looked at 20 adults in the ICU who were on breathing machines (ventilators) and ready to try breathing on their own. Researchers compared two methods: one using low pressure support and another using automatic tube compensation (ATC) to offset the tube's resistance. The goal was to see which method better measures the patient's true breathing effort. This was a small, completed study that helps refine weaning techniques.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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20 people
The number who actually took part.
- Started
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Aug 2017
- Finished
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Oct 2018
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * age 18 years or more * intubated and mechanically ventilated for at least 24 consecutive hours * staying in the medical ICU at the Croix Rousse Hospital, Lyon, France * pressure support ventilation 10-15 cm H2O, total respiratory rate 25-35 breaths/min, expired tidal volume 6-8 ml/kg predicted body weight * meeting criteria for spontaneous breathing trial (able to answer simple questions, no ongoing intravenous sedation, norepinephrine ≤ 1 mg/H, dobutamine ≤ 20 mg/h, fraction of inspired oxygen (FIO2 ≤ 50%), PEP ≤ 5 cm H2O, respiratory rate ≤ 35 breaths/min, saturation in oxygen (SpO2) ≥88%) * under Dräger Evita XL ou V500 ICU ventilator * agreement to participate from the patient or next of kin Exclusion Criteria: * Chronic respiratory failure under long term home oxygen therapy and/or non invasive ventilation before ICU admission * Tracheotomy * nasogastric tube contra-indicated * thoracic tube in place * no agreement to participate * under justice protection * deprived of freedom * pregnant or breastfeeding * not affiliated to social insurance * involved into another study that may interfere with present study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hôpital de la Croix Rousse
Lyon, 69004, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.