New anesthesia combo may improve safety during lung procedures
NCT ID NCT07409935
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether adding dexmedetomidine to propofol during rigid bronchoscopy (a procedure to examine the airways) leads to more stable heart rates and fewer complications. Fifty adults were randomly assigned to receive either propofol alone or propofol plus dexmedetomidine. The goal was to see if the combination could improve safety and recovery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- propofol and dexmedetomidine
- What this could lead to
- If successful, this could lead to a more stable and safer anesthesia method for rigid bronchoscopy procedures.
- What could go wrong
- This is a small, completed Phase 4 trial with only 50 participants, so results may not apply to all patients. The study focuses on short-term outcomes, not long-term benefits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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50 people
The number who actually took part.
- Started
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Apr 2024
- Finished
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Oct 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged 18 - 60 years, scheduled for elective rigid bronchoscopy procedure. * ASA physical status I-II * Both genders. Exclusion Criteria: * Patient refusal. * Known allergy to any of the used drugs. * Bleeding disorders. * Hemodynamically unstable patients ( mean arterial blood pressure \[MAP\] \< 60 mmHg). * Tracheostomy tube in situ. * Patients with stridor and any upper airway emergency.
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cairo University
Cairo, Cairo Governorate, Egypt