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Heat and radiation team up to fight spine cancer

NCT ID NCT02713269

First seen Nov 01, 2025 · Last updated Jun 20, 2026 · Updated 25 times

Summary

This study tests whether combining two treatments—thermal ablation (using heat to destroy tumor cells) and stereotactic radiosurgery (precise, high-dose radiation)—can better control cancer that has spread to the spine and is pressing on the spinal cord. About 60 adults with various solid tumors are participating. The goal is to see if this combination improves local tumor control and reduces the risk of spinal cord compression.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

thermal ablation and stereotactic radiosurgery

What this could lead to

If successful, this combination could offer a more effective way to control spine tumors and prevent spinal cord compression, improving quality of life for patients with advanced cancer.

What could go wrong

This is a small, early-phase trial with only 60 participants, so results may not apply to all patients. The combination also carries risks like nerve damage or pain from the procedures.

Conditions

The condition(s) this trial relates to.

breast cancer cancer of unknown primary site digestive system cancer digestive system neoplasm head and neck carcinoma invasive breast carcinoma melanoma metastatic malignant neoplasm in the spinal cord metastatic melanoma metastatic prostate carcinoma neoplasm Neoplasms, Unknown Primary non-small cell lung carcinoma renal carcinoma renal cell carcinoma sarcoma Spinal Cord Compression thyroid gland carcinoma Thyroid Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.