MALIGNANT DIGESTIVE SYSTEM NEOPLASM

This study tests a new tool called the PAGODA algorithm to help doctors adjust chemotherapy doses proactively. The goal is to reduce unplanned treatment delays in people with gastrointestinal cancers receiving FOLFOX chemotherapy. About 420 participants will be randomly assigned …

This study compares giving the chemotherapy drug oxaliplatin over 2 hours versus 6 hours to see if the longer infusion reduces nerve damage. About 60 people with gastrointestinal cancers who are scheduled for at least 4 cycles of FOLFOX6 chemotherapy will participate. The goal is…

This study tests whether fucoidan, a supplement from brown seaweed, can reduce fatigue caused by chemotherapy in people with gastrointestinal or gynecological cancer. About 34 participants will take either fucoidan or a placebo for 16 weeks and report their fatigue levels. The go…

This study looks at how safe and helpful it is to place a stent in the portal vein of people with gastrointestinal cancer whose vein has become narrowed. Researchers want to see how long the stent stays open and how it affects patients' overall well-being, including nutrition, bl…

This study is gathering information on side effects from proton therapy in 5,000 adults with various cancers. Researchers will collect detailed treatment and toxicity data to better understand and predict short- and long-term side effects. The goal is to improve future patient ca…

This study surveys 500 surgeons and advanced practice providers to see how often they prescribe blood clot prevention medication after abdominal or pelvic cancer surgery. The goal is to understand current practices and improve adherence to guidelines. No patients receive treatmen…

This study looks at what causes biliary tree cancers by examining environmental, viral, and genetic factors. Researchers will study 1500 people, including patients and healthy volunteers, to find markers that predict cancer development and treatment response. The goal is to bette…