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Knee cartilage repair gets a boost from collagen mesh

NCT ID NCT07352410

Disease control Sponsor: Adichunchanagiri Institute of Medical Sciences, B G Nagara Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding a special collagen mesh during knee surgery helps repair torn meniscus cartilage. 18 adults with meniscal tears had the mesh placed over the repair site. The goal was to see if it was safe and could improve healing. This was a small, early-stage study to gather information for a larger trial.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
High-Purity Type I Collagen mesh
What this could lead to
If it works, this could lead to a better way to repair torn knee cartilage, potentially reducing pain and improving knee function.
What could go wrong
This was a very small, early feasibility study with only 18 people and no comparison group. The results may not apply to everyone, and there is a risk of infection or inflammation from the collagen.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

18 people

The number who actually took part.

Started

Jan 2026

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 55 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 to 55 years * Symptomatic meniscal tear confirmed on MRI and indicated for arthroscopic repair * Tear patterns amenable to repair * Stable knee or concomitant ACL reconstruction permitted * Ability to comply with rehabilitation and follow-up * Written informed consent provided Exclusion Criteria: * Advanced knee osteoarthritis (Kellgren-Lawrence grade ≥3) * Irreparable meniscal tears requiring meniscectomy * Active joint infection or inflammatory arthritis * Prior surgical repair of the index meniscus * Known hypersensitivity to collagen products * Systemic conditions impairing wound healing

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Conditions

The condition(s) this trial relates to.

Knee Injuries Osteogenesis Imperfecta, Type IV

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee arthroscopy (for diagnostic or therapy) Knee meniscus injury Meniscal repair Meniscus tear

Contacts and locations

Locations

  • Adichunchanagiri Institute of Medical Sciences

    Mandya, Karnataka, 571448, India

More trials for these conditions

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