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Chill training: could 8 days of cold boost your grip?

NCT ID NCT05464758

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether spending 120 minutes in 8°C air for 8 days in a row helps the body adapt to cold. Researchers measured blood flow, hand strength, dexterity, and comfort in 16 healthy adults. The goal is to find ways to keep hands working well in cold conditions, which could help soldiers and others in cold environments.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Repeated cold exposure
What this could lead to
If successful, this could point toward simple training methods to help people maintain hand function and comfort in cold environments.
What could go wrong
This is a small, early-stage study with only 16 healthy adults, so results may not apply to broader populations or real-world conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

16 people

The number who actually took part.

Started

Aug 2022

Finished

Sep 2024

Lead sponsor

A government agency

The lead sponsor is a US federal agency other than the NIH.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 39 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female, age 18-39 * In good health as determined by OMSO (Office of Medical Support and Oversight) * Willing to refrain from exercise and caffeinated or alcoholic beverages for 12 hours before each testing session * Willing to refrain from smoking or tobacco use 8 hours before each testing session Exclusion Criteria: * History of cold injuries of any severity (e.g., frostbite, trench foot, chilblains). * Raynaud's syndrome. * Cold-induced asthma/bronchospasm * Previous hand/finger injuries that impair dexterity and hand function. * Metal hardware (plates/screws) in the forearms and hands. * Current use of medications or dietary supplements that could alter cardiovascular, thermoregulatory, or vascular control (e.g., anti-hypertensives, statins). * Known allergies to medical adhesives. * Heart, lung, kidney, muscle, or nerve disorder(s) * A planned MRI during the study or within 2 days after completing a cold test. * Women who are pregnant, planning to become pregnant, or breastfeeding. * Not willing to have small areas of skin on the body shaved (if deemed necessary for attachment of study instrumentation)

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • U.S. Army Research Institute of Environmental Medicine

    Natick, Massachusetts, 01760, United States

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