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Skin biopsy may reveal hidden aneurysm risk in gene mutation carriers

NCT ID NCT07282717

First seen Jan 05, 2026 · Last updated May 25, 2026 · Updated 21 times

Summary

This study enrolls 20 adults with COL5A gene mutations to explore why some develop aortic aneurysms and others do not. Researchers will take a small skin sample and study the cells to compare collagen production and tissue structure. The goal is to find biological clues that could lead to personalized monitoring and care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cardiovascular Genetic Centre IRCCS Policlinico San Donato

    San Donato Milanese, Italy, 20097, Italy

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.