Brain games may shield seniors with diabetes from memory loss
NCT ID NCT06524388
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a computerized brain-training program can improve thinking skills in older adults (60+) who have type 2 diabetes and are at high risk for dementia. 120 participants will be randomly assigned to either adaptive cognitive training or a placebo version, both delivered on a tablet. The training lasts 6 months, and researchers will measure changes in memory, attention, and other cognitive functions using the MoCA test.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- adaptive cognitive training (computerized brain exercises)
- What this could lead to
- If it works, this could point toward a simple, non-drug way to help older adults with diabetes keep their thinking sharp and possibly delay dementia.
- What could go wrong
- This is a small, early-stage trial with only 120 participants, so results may not apply to everyone. The training is time-consuming, and improvements may be modest or not last long.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2024
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * with a clear diagnosis of diabetes (according to ICD-10 or DSM-criteria), fasting blood glucose≥6.1mmol/L, maintaining the original diabetes treatment strategy * age ≥60 years old * literate and able to use smart phone or tablet computer skillfully, with CAIDE dementia risk score \>9, but without a diagnosis of dementia (ICD-10 or DSM-dementia diagnostic criteria) * have lived in the target community for at least 6 months and continue to live in the original community for the next 12 months Exclusion Criteria: * Stroke or brain surgery in the previous 12 months * Alcohol or drug abuse in the past 12 months * Families, important people of participants in the study have concerns * Live in the same household as a participant who has been randomly assigned * Severe aphasia, physical disability, or any other factor that may prevent completion of neuropsychological testing * Use of medications that may affect cognition, including sedatives, anxiolytics, hypnotics, nootropics, and cholinergic drugs; Refusing or not receiving cognitive training * currently participating in another clinical trial.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Xihuangcun Hospital
Beijing, 100144, China
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