Brain games may rev up thinking and driving after cancer treatment
NCT ID NCT07740616
First seen Jul 31, 2026 · Last updated Jul 31, 2026
Summary
This study tests whether a 10-week home-based video game training program can improve cognitive function and driving performance in head and neck cancer survivors who report thinking difficulties after radiation or chemoradiation. Participants will complete questionnaires, use a driving simulator, and play either adaptive cognitive training games or non-adaptive sham games twice a week. The goal is to see if the training speeds up visual processing and attention, which could translate to safer driving.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Speed of Processing Training (game-based cognitive exercises)
- What this could lead to
- If effective, this training could offer a practical, home-based way to sharpen thinking and improve driving safety for head and neck cancer survivors.
- What could go wrong
- This is a small early-stage study, so results may not apply broadly. The training may not produce lasting improvements, and benefits could vary from person to person.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 89 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * confirmed HNC diagnosis * aged ≥ 18 years of all racial, ethnic, and sex/gender categories * ≥ 6 months post radiation or chemoradiation * self-reported CRCI, defined as a score of ≥ 60 in the FACT-Cog Perceived Cognitive Impairment subscale * thyroid-stimulating hormone levels within normal limits * visual acuity of at least 20/40 using a Snellen eye chart * functional peripheral vision as indicated by the confrontation field test * functional hearing sufficient to engage in daily conversation in English for ≥ 15 minutes * intact lower extremity function (Rapid Pace Walk test ≤ 9 sec) * stable home internet * sufficient English proficiency to read and understand informed consent materials Exclusion Criteria: * significant neurologic or psychiatric comorbidities, including psychotic disorders, bipolar disorders, Alzheimer's disease or related dementias, developmental disorders, seizure disorders, vestibular disorders, prior brain tumor or brain surgery, or poorly controlled metabolic disease * current use of antipsychotic or mood-stabilizing medications due to potential effects on driving performance * anticipated life expectancy of \< 6 months based on physician prognosis.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
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