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Stroke recovery at home: brain training may cut dementia risk

NCT ID NCT07251517

Disease control Sponsor: University of Florence Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a 40-hour, 8-week cognitive telerehabilitation program could reduce the risk of memory and thinking problems after a stroke. 86 adults who recently had a stroke were randomly assigned to either the home-based brain training or standard care. The program included exercises for memory, attention, and problem-solving. Researchers measured cognitive impairment, daily living skills, and quality of life six months later.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
cognitive telerehabilitation program
What this could lead to
If it works, this could provide an effective, convenient way to prevent or reduce cognitive decline after a stroke, improving daily life and independence.
What could go wrong
This is a relatively small, completed trial, so results may not apply to all stroke survivors. The intervention requires significant time commitment, and benefits may not persist long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

86 people

The number who actually took part.

Started

Apr 2024

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 years * Diagnosis of ischemic or hemorrhagic stroke between 5 and 21 days after the event * Ability to express written informed consent * Evidence of impairment of global cognitive efficiency according to the post-stroke MoCA (MoCA total score≤21) * Normal stenia of at least one upper limb (NIHSS motor item of at least one upper limb=0) Exclusion Criteria: * Pre-existing dementia (IQ-CODE\>3.48 and/or diagnosis of dementia by a specialist). * Severe aphasia (NIHSS language item ≥2 and impaired performance on the Token test, i.e. a correct score below the 5th centile of the normal population). * Withdrawal of informed consent

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction hemorrhagic stroke ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognitive impairment Stroke, acute

Contacts and locations

Locations

  • University of Florence

    Florence, Firenze, 50134, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.