Brain and body boost: could home-based cognitive and physical training ease 'chemo brain' after breast cancer?
NCT ID NCT04213365
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This study explores whether a 12-week program combining cognitive stimulation sessions and adapted physical activity, done at home with remote supervision, is feasible for women who have cognitive difficulties after breast cancer treatment. The study includes 20 women with localized breast cancer who report significant cognitive complaints affecting their quality of life. The goal is to see if patients can stick with the program and find it acceptable, before testing its effectiveness in larger trials.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- cognitive stimulation sessions and adapted physical activity sessions
- What this could lead to
- If feasible, this combined approach could point toward a practical, home-based program to ease cognitive difficulties after breast cancer treatment.
- What could go wrong
- This is a small feasibility study with only 20 participants, so it cannot prove effectiveness. The program may not be practical or acceptable for many patients.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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20 people
The number who actually took part.
- Started
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Jan 2020
- Finished
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Feb 2022
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient aged over 18, * Patient with localized breast cancer, starting or receiving adjuvant radiotherapy , having or not receiving previous adjuvant chemotherapy, not yet having started hormone therapy, * Patient with a cognitive complaint having a significant impact on her quality of life (FACT * Cog questionnaire, QoL score ≤ percentile 10 by age), * Absence of major cognitive impairment preventing the performance of cognitive tests (compliance with the MoCA score threshold according to the age and educational level of the patient according to GRECOGVASC standards) * Absence of personality disorders and known progressive psychiatric pathology (e.g. schizophrenia), * Absence of symptomatic neurological history (neurological sequelae of a head trauma, stroke with loss of consciousness\> 30 min, multiple sclerosis, epilepsy, neurodegenerative pathology, etc.), * Patient with level of education 3 "end of primary education" minimum (Barbizet scale), * Have access to a computer (fixed or portable) equipped with a keyboard, a webcam (or the possibility of connecting one), headphones or speakers; have an internet connection and an e-mail account; be able to use these tools and Equipment, * Mastery of the French language, * Patient who signed the consent to participate in the study. * Patients should start the study during radiation therapy. Exclusion Criteria: * Abuse of alcohol or drug use, * Severe visual and / or hearing loss, * Patient unable to respond to cognitive tests, * Medical contraindication to the practice of adapted physical activity * Cognitive management in progress, * Patient's refusal to participate, * Patient deprived of liberty or under guardianship, * Patient unable to submit to study monitoring for geographic, social or psychopathological reasons.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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centre François Baclesse
Caen, 14076, France
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Other studies related to the condition(s) this trial covers.
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