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Brain and body boost: could home-based cognitive and physical training ease 'chemo brain' after breast cancer?

NCT ID NCT04213365

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study explores whether a 12-week program combining cognitive stimulation sessions and adapted physical activity, done at home with remote supervision, is feasible for women who have cognitive difficulties after breast cancer treatment. The study includes 20 women with localized breast cancer who report significant cognitive complaints affecting their quality of life. The goal is to see if patients can stick with the program and find it acceptable, before testing its effectiveness in larger trials.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
cognitive stimulation sessions and adapted physical activity sessions
What this could lead to
If feasible, this combined approach could point toward a practical, home-based program to ease cognitive difficulties after breast cancer treatment.
What could go wrong
This is a small feasibility study with only 20 participants, so it cannot prove effectiveness. The program may not be practical or acceptable for many patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

20 people

The number who actually took part.

Started

Jan 2020

Finished

Feb 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient aged over 18, * Patient with localized breast cancer, starting or receiving adjuvant radiotherapy , having or not receiving previous adjuvant chemotherapy, not yet having started hormone therapy, * Patient with a cognitive complaint having a significant impact on her quality of life (FACT * Cog questionnaire, QoL score ≤ percentile 10 by age), * Absence of major cognitive impairment preventing the performance of cognitive tests (compliance with the MoCA score threshold according to the age and educational level of the patient according to GRECOGVASC standards) * Absence of personality disorders and known progressive psychiatric pathology (e.g. schizophrenia), * Absence of symptomatic neurological history (neurological sequelae of a head trauma, stroke with loss of consciousness\> 30 min, multiple sclerosis, epilepsy, neurodegenerative pathology, etc.), * Patient with level of education 3 "end of primary education" minimum (Barbizet scale), * Have access to a computer (fixed or portable) equipped with a keyboard, a webcam (or the possibility of connecting one), headphones or speakers; have an internet connection and an e-mail account; be able to use these tools and Equipment, * Mastery of the French language, * Patient who signed the consent to participate in the study. * Patients should start the study during radiation therapy. Exclusion Criteria: * Abuse of alcohol or drug use, * Severe visual and / or hearing loss, * Patient unable to respond to cognitive tests, * Medical contraindication to the practice of adapted physical activity * Cognitive management in progress, * Patient's refusal to participate, * Patient deprived of liberty or under guardianship, * Patient unable to submit to study monitoring for geographic, social or psychopathological reasons.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • centre François Baclesse

    Caen, 14076, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.