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Coffee vs. AFib: can ditching your morning cup keep your heart in rhythm?

NCT ID NCT05121519

Disease control Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether stopping coffee helps prevent atrial fibrillation (AFib) from returning after a heart shock treatment called cardioversion. Two hundred coffee drinkers with AFib were randomly assigned to either keep drinking coffee or avoid it for six months. Researchers tracked how many people in each group had another AFib episode.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
coffee
What this could lead to
If quitting coffee reduces AFib recurrence, it could offer a simple lifestyle change to help manage the condition.
What could go wrong
This is a small, completed trial. Results may not apply to everyone, and quitting coffee might not make a difference for all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

200 people

The number who actually took part.

Started

Oct 2021

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Men or women ≥ 21 years of age * Sustained AF or atrial flutter (provided patient has a history of AF) * Planned/scheduled direct current electrical cardioversion * Consumption greater than or equal to one cup of coffee per day sometime in the past 5 years * Willing and able to comply with coffee abstinence or continuation for at least 6 months * Life expectancy of at least 6 months * Willing and able to return and comply with scheduled phone follow up visits * Willing and able to provide written informed consent Exclusion Criteria: * Established allergy or adverse reaction to coffee * Stated inability to comply with coffee abstinence or continuation * AF ablation in preceding 3 months or planned in next 3 months * Recent cardiothoracic surgery in preceding 3 months * Pregnancy or desire to get pregnant within next 6 months. * Current enrollment in an investigation or study of a cardiovascular device or investigational drug that would interfere with this study * Any other criteria, which would make the patient unsuitable to participate in this study as determined by the Principal Investigator (e.g., an uncontrolled drug and/or alcohol addiction)

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Conditions

The condition(s) this trial relates to.

atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atrial fibrillation COFFEE

Contacts and locations

Locations

  • Royal Adelaide Hospital

    Adelaide, Australia

  • Sunnybrook Health Science Centre

    Toronto, Canada

  • UCSF Parnassus

    San Francisco, California, 94143, United States

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