New drug tested for tough liver disease

NCT ID NCT05104853

Completed Disease control Sponsor: COUR Pharmaceutical Development Company, Inc. Source: ClinicalTrials.gov ↗

Summary

This study tested an experimental drug called CNP-104 in adults with primary biliary cholangitis (PBC), a chronic liver disease, who weren't responding well to standard medications. Forty-two participants received either CNP-104 or a placebo infusion to check its safety and see if it could improve liver health and symptoms like itching over two years of follow-up.

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Contacts and locations

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Locations

Cleveland Clinic - Florida

Weston, Florida, 33331, United States
Digestive Healthcare of Georgia

Atlanta, Georgia, 30309, United States
Duke University Medical Center

Durham, North Carolina, 27710, United States
Florida Research Institute

Lakewood Rch, Florida, 34211-4930, United States
GI PROS Research

Naples, Florida, 34102, United States
Henry Ford Health System

Novi, Michigan, 48377, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
Mayo Clinic Florida

Jacksonville, Florida, 32224, United States
Montefiore Medical Center

The Bronx, New York, 10467, United States
OM Research

Lancaster, California, 93534, United States
Peak Gastroenterology Associates

Colorado Springs, Colorado, 80907, United States
Southern California Research Center

Coronado, California, 92118, United States
Texas Liver Institute

San Antonio, Texas, 78215, United States
University of California Davis Health

Sacramento, California, 95817, United States
University of Chicago Medical Center

Chicago, Illinois, 60637, United States
University of Florida - Hepatology Research

Gainesville, Florida, 32610, United States
University of Virginia

Charlottesville, Virginia, 22903, United States
Washington University School of Medicine in St. Louis

St Louis, Missouri, 63110, United States
Yale School of Medicine

New Haven, Connecticut, 06520, United States

Conditions

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PRIMARY BILIARY CHOLANGITIS