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New hope: clozapine may curb violence in schizophrenia patients

NCT ID NCT05208190

First seen Jan 07, 2026 · Last updated May 01, 2026 · Updated 18 times

Summary

This study tests whether clozapine, a medication for schizophrenia, can lower the risk of violent acts better than usual antipsychotic treatments. About 280 adults with schizophrenia or schizoaffective disorder who have been violent in the past six months will take either clozapine or standard medication for 24 weeks. Researchers will track violent behavior and other symptoms to see which approach works best.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Augusta University Research Institute, Inc.

    RECRUITING

    Augusta, Georgia, 30912, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Manhattan Psychiatric Center

    RECRUITING

    New York, New York, 10035, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NYU Langone Medical Center

    RECRUITING

    New York, New York, 10016, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • New York State Psychiatric Institute

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • University of California, Los Angeles

    RECRUITING

    Los Angeles, California, 90024, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Maryland School of Medicine

    RECRUITING

    Baltimore, Maryland, 21201, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.