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Blood thinners may be safe during retina surgery, study suggests

NCT ID NCT03863548

Knowledge-focused Sponsor: Centre Hospitalier Universitaire Dijon Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed French study followed 748 adults undergoing retina/vitreous surgery to see if taking blood thinners (anticoagulants or antiplatelets) raises the risk of bleeding complications. Researchers compared patients who continued or stopped their medication with those not on blood thinners. The goal is to provide clearer guidance on whether it's safe to keep taking these drugs around the time of surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If the hypothesis holds, it could help doctors decide it's safe to continue blood thinners during retina/vitreous surgery, reducing patients' risk of stroke or heart attack.
What could go wrong
This is an observational study, not a controlled trial, so it can't prove cause and effect. Results may not apply to all surgery types or patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

748 people

The number who actually took part.

Started

Jan 2019

Finished

Jul 2019

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients undergoing surgery

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * person who has expressed willingness to participate * person over 18 years of age * person with a retinal-vitreous condition requiring scheduled surgery (epi-retinal membrane surgery, vitreous traction surgery, macular hole surgery). Exclusion Criteria: * person subject to legal protection (curatorship, guardianship) * person deemed mentally incompetent * pregnant, parturient or breastfeeding woman * adult unwilling or unable to consent * patient who has already participated in the study * person with a physical or mental disability that does not allow participation. * a person who has participated in any study of an experimental medical product within the previous 3 months * person who experiences any of the following during the ophthalmological examination: * severe or proliferating diabetic retinopathy * intra-vitreal hemorrhage * tractional retinal detachment * subretinal or retrohyaloidal hematoma.

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Conditions

The condition(s) this trial relates to.

macular holes preretinal fibrosis vitreous detachment

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Patients undergoing retina/vitreous surgery

Contacts and locations

Locations

  • CHU dijon Bourgogne

    Dijon, 21000, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.