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Scientists probe eye fluids to unlock secrets of retinal detachment

NCT ID NCT06347302

Knowledge-focused Sponsor: Centre Hospitalier Universitaire Dijon Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at fluid samples from the eyes of 137 people undergoing surgery for retinal detachment or other eye conditions. Researchers measured fats and proteins in these fluids to understand inflammation and cell death that can harm vision after surgery. The goal is to find clues that could lead to better treatments and improve visual outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could point toward new therapies that improve vision recovery after retinal detachment surgery.
What could go wrong
This is an observational study, not a treatment trial. The findings may not lead to immediate clinical changes, and further research is needed to confirm any links.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

137 people

The number who actually took part.

Started

Apr 2024

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Subject having given oral, free and informed consent to take part in the study * Subjects with primary retinal detachment requiring vitrectomy (RD group) Or * Subject requiring vitrectomy for macular surgery (primary epiretinal membrane or macular hole) (Control group) Exclusion Criteria: * Subject not affiliated to or not benefiting from national health insurance * Pregnant, parturient or breast-feeding women * Minors * Subject to a measure of legal protection (curatorship, guardianship) * Subjects of full age who are incapable or unable to express their consent * Subject who has already participated in the study * Subject with recurrent retinal detachment * Subjects with an epiretinal membrane of secondary origin (OVCR, inflammation, diabetic retinopathy) * Subject refusing blood sampling * Subjects with pre-existing retinal pathology (vascular or degenerative retinopathy) * People with diabetes

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Conditions

The condition(s) this trial relates to.

macular holes preretinal fibrosis rhegmatogenous retinal detachment

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Rhegmatogenous retinal detachments

Contacts and locations

Locations

  • Chu Dijon Bourgogne

    Dijon, 21000, France

More trials for these conditions

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