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Eye drops before surgery may boost vision recovery

NCT ID NCT07736690

Symptom relief Sponsor: Ankara Yildirim Beyazıt University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This trial tests whether adding nepafenac eye drops before and after surgery for epiretinal membrane (a wrinkle on the retina) can help the eye heal faster. Sixty adults with this condition will either receive the drops plus standard care or standard care alone. Researchers will measure vision sharpness and retinal thickness over six months to see if the drops make a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
nepafenac 0.1% eye drops
What this could lead to
If it works, this could mean faster visual recovery and less swelling after epiretinal membrane surgery.
What could go wrong
This is a small, single-center study, so results may not apply widely. Eye drops can cause irritation or side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

60 people

The number who actually took part.

Started

Jan 2024

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria:- * Adults aged 18 years or older. * Diagnosis of idiopathic epiretinal membrane requiring pars plana vitrectomy. * Best-corrected visual acuity impairment and/or metamorphopsia attributed to epiretinal membrane. * Ability to provide written informed consent. * Willingness to complete the scheduled follow-up examinations for 6 months. Exclusion Criteria: * \- Previous vitreoretinal surgery in the study eye. * Other retinal diseases that could affect visual or anatomical outcomes (e.g., diabetic retinopathy, retinal vein occlusion, age-related macular degeneration). * Significant ocular trauma. * Active ocular inflammation or infection. * Advanced glaucoma or optic neuropathy affecting visual function. * Media opacity preventing adequate retinal imaging.

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Conditions

The condition(s) this trial relates to.

preretinal fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Epiretinal membrane Macular pucker

Contacts and locations

Locations

  • Ankara Bilkent City Hospital

    Ankara, Ankara, 06800, Turkey (Türkiye)

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Other studies related to the condition(s) this trial covers.