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Closed suctioning may keep ICU patients more stable and less painful

NCT ID NCT06143865

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This completed study from Turkey tested whether a closed suction system (a catheter that stays inside the breathing tube) causes less change in blood pressure, heart rate, breathing, and oxygen levels, and less pain, compared to usual care. The study included 67 adults on mechanical ventilators who were not sedated. Researchers measured vital signs and pain scores at three time points. The results could help nurses decide if closed suctioning is better for patient comfort and safety.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Closed system aspiration (a suction catheter inside a protective sheath, used repeatedly during the day)
What this could lead to
If the results show closed aspiration causes fewer changes in vital signs and less pain, it could support using this method routinely in ICUs to improve patient comfort and safety.
What could go wrong
This is a small, single-center study with only 67 participants, so findings may not apply to all ICU patients. The study is already completed, so it only provides observational data, not proof of a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

67 people

The number who actually took part.

Started

Jul 2022

Finished

Oct 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * over 18 years, * Intubated * Connected to mechanical ventilator, * Not receiving sedation, * Not unconscious, * Monitored, * Systolic arterial blood pressure is between 110-140 mmHg and diastolic arterial blood pressure is between 60-90 mmHg, * Heart rate between 60-100/min, * Respiratory rate between 12-20/min, * Body temperature not higher than 38º C, * Oxygen saturation level (SpO2) \>86% Exclusion Criteria: * Not intubated, * Received a diagnosis related to the respiratory system, * Unconscious or sedated curare

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Conditions

The condition(s) this trial relates to.

Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Elif Günay İsmailoğlu

    Izmir, Menemen, 35160, Turkey (Türkiye)

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