Can a different suctioning order cut pneumonia risk in ventilated patients?
NCT ID NCT01807884
First seen Sep 17, 2026 · Last updated Sep 18, 2026 · Updated 1 time
Summary
Researchers compare two ways of clearing secretions from the mouth and windpipe in patients on breathing machines. One routine adds subglottic suctioning in a specific sequence; the other uses standard oral suction and mouth care. The trial measures a marker of fluid leaking into the lungs to see if the optimized routine lowers that risk.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- optimized oral and tracheal suctioning procedure using a subglottic drainage device
- What this could lead to
- If the optimized routine lowers microaspiration, it could inform a simple, low-cost way to reduce ventilator-associated pneumonia in intensive care.
- What could go wrong
- This is a small pilot trial with 24 patients, so it may not show a clear difference or predict results in a larger, more diverse group. The amylase ratio is a surrogate marker, not a direct measure of pneumonia.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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24 people
The number who actually took part.
- Started
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Nov 2014
- Finished
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Mar 2016
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Intubated with a subglottic secretion drainage device * ventilated more than 48 hours * patients yielding a significant tracheal suctioning volume (on a semi-qualitative evaluation: ≥ ++ on a scale consisting of 0,+,++,+++) Exclusion Criteria: * paralysed patients * patients with Ramsay 1, 2 * patients breathing spontaneously * patients less than 18 years old * patients in a moribund state * contra-indication for suctioning procedure (risk of haemorrhage, bronchospasm, Acute Respiratory Distress Syndrome with P/F \< 100, malformation or tracheal fistula) * bronchiectasis, cystic fibrosis, chronic obstructive pulmonary disease * patients necessitating a closed-suctioning device (prevention of respiratory multiresistant bacteria transmission, Acute Respiratory Distress Syndrome with P/F ratio \< 100) * pregnant women
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hospital Pellegrin
Bordeaux, Gironde, 33000, France
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