Fertility drug may give men with zero sperm a second chance at fatherhood
NCT ID NCT03615547
First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 31 times
Summary
This study tests whether taking clomiphene citrate (a hormone pill) for 9 months before a second surgical sperm retrieval helps men who have no sperm in their semen (non-obstructive azoospermia) and had a failed first retrieval. About 128 men will be randomly assigned to receive the drug or a placebo. The goal is to see if more men can find at least one usable sperm for IVF. This is a phase 3 trial, meaning it is in the final stage of testing before possible widespread use.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hospices Civils de Lyon, Hôpital Femme-Mère-Enfant
Bron, France
Contact Email: •••••@•••••
Conditions
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