Fertility drug may give hope to men with zero sperm

NCT ID NCT03615547

First seen Nov 01, 2025 · Last updated May 10, 2026 · Updated 28 times

Summary

This study tests whether taking clomiphene citrate (a fertility drug) for 9 months can help men with non-obstructive azoospermia (no sperm in semen due to testicular failure) produce sperm for IVF. About 128 men who had a failed first sperm retrieval surgery will receive either the drug or a placebo. The goal is to see if more men can have sperm found in their semen or during a second surgery, offering a chance at biological fatherhood.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospices Civils de Lyon, Hôpital Femme-Mère-Enfant

    Bron, France

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.