Do faster aligner changes harm your roots? new study investigates
NCT ID NCT07522216
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether changing clear aligners every 7 days or every 14 days affects tooth root shortening and pain. Fifty-two adults with mild to moderate crowding are randomly assigned to one of two wear schedules. Researchers measure root length from X-rays taken before and after treatment, and track pain levels. The goal is to find out which schedule is safer for tooth roots.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- orthodontic clear aligner wear protocol (7-day vs 14-day)
- What this could lead to
- If successful, this could help orthodontists choose the safest aligner wear schedule to minimize root damage and discomfort.
- What could go wrong
- This is a small, early-stage study with only 52 participants, so results may not apply to everyone. Root resorption is a known risk of orthodontic treatment regardless of wear protocol.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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52 people
The number who actually took part.
- Started
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Feb 2025
- Expected to finish
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May 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 30 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participants with complete permanent dentition except wisdom teeth * Participants presented with mild to moderate malocclusion (Average degree of crowding). * Participants with good oral hygiene and absence of periodontal disease. * No history of trauma or prior orthodontic treatment. Exclusion Criteria: * Participants with thin or petite roots. * Participants with pre-existing root resorption * Participants with endodontically treated incisors or canines. * Participants with history of trauma to incisors teeth * Participants with previous orthodontic treatment. * Participants with periapical pathology, ankylosisor cystic lesions. * Participants with medical conditions that may affecting pain or inflammatory responses.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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postgraduate orthodontic clinics at JUST
Irbid, 22110, Jordan
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