Which clear aligner holds up better? new study puts materials to the test
NCT ID NCT07566533
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at two types of clear aligners used to straighten teeth: single-layer and triple-layer plastic sheets. 66 people wore them for 10 days, and researchers tested how the aligners' strength, flexibility, and surface changed. The goal is to see which material holds up better inside the mouth, which could lead to more effective orthodontic treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Thermoplastic polyurethane (TPU) clear aligners
- What this could lead to
- If successful, this could help improve the design of clear aligners for better durability and force retention during orthodontic treatment.
- What could go wrong
- This is a small, completed study focused on material properties, not on clinical outcomes like tooth movement. Results may not directly translate to better treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
66 people
The number who actually took part.
- Started
-
Sep 2025
- Finished
-
Mar 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 30 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Patients aged 18-30 years Fully erupted permanent dentition Good periodontal health Patients undergoing orthodontic treatment with clear aligners Mild crowding or spacing requiring labiolingual tooth movement Willingness to wear aligners for at least 22 hours per day Provision of informed consent Exclusion Criteria: Use of aligners from manufacturers other than study-specific TPU aligners Damaged or fractured aligners Poor compliance (wear time less than 22 hours/day) Presence of parafunctional habits (e.g., bruxism) Hypodontia or partially erupted dentition Cases involving bonded attachments on maxillary incisors Cases requiring rotational movement of maxillary incisors Patients with systemic or oral conditions affecting saliva composition or the oral environment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Akhtar Saeed Medical & Dental College
Lahore, Punjab Province, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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