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Could a pill replace chemo for some breast cancer patients?

NCT ID NCT07432178

First seen Mar 17, 2026 · Last updated Jun 18, 2026 · Updated 11 times

Summary

This study tests whether a chemotherapy-free treatment using the targeted drug Dalpiciclib (a CDK4/6 inhibitor) plus hormone therapy works as well as standard chemotherapy for women with small, high-risk, hormone-receptor-positive breast cancer. About 2,288 participants will be randomly assigned to either the new drug combo or standard chemo, both followed by hormone therapy. The goal is to see if the new approach can prevent cancer from coming back while avoiding chemotherapy's harsh side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.