Meal timing may be key to Long-Term success after Weight-Loss surgery
NCT ID NCT07324044
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether eating meals at times that match your body's internal clock can help people who have had weight-loss surgery keep the weight off and improve their health. About 246 adults who had sleeve gastrectomy at least six months ago will either follow standard dietary advice or a personalized meal-timing plan based on whether they are a morning or evening type. Researchers will track weight, blood sugar, gut bacteria, and sleep patterns over a year to see if this approach makes a difference.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- chrono-nutrition (personalized meal timing based on chronotype)
- What this could lead to
- If it works, this could point toward a simple, drug-free way to help people keep weight off and improve metabolic health after bariatric surgery.
- What could go wrong
- This is an early-stage trial with no results yet. The benefit may be small or not apply to everyone, and sticking to strict meal times can be hard for some people.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 246 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18-50 years who underwent Sleeve Gastrectomy (SG) 6 Months prior to enrollment. * Have achieved ≥50% of excess weight loss post-surgery (to ensure initial success). * Current BMI between 25-40 kg/m². * No major postoperative complications and cleared for a regular diet by their healthcare provider. * Participants must be able to align their eating schedule within a daytime window (morning to evening), ensuring that the first meal is consumed in the early part of the day and the last meal is completed before late evening, in accordance with chrono-nutrition guidelines. Exclusion Criteria: * • Pregnancy or planned pregnancy during the study period, and post menopaused females * Current diagnosis of severe psychiatric illness that may interfere with adherence (e.g., untreated major depression, psychosis, severe eating disorders). * Active malignancy or serious chronic disease unrelated to obesity that may confound outcomes (e.g., advanced renal failure, uncontrolled liver disease). * Use of medications known to significantly alter circadian rhythm or metabolism (e.g., corticosteroids, melatonin therapy) within the last 3 months. * Inability to comply with study requirements (dietary interventions, sample collection, or follow-up visits).Participants who have previously undergone revision bariatric surgery. * Individuals following intermittent fasting regimens prior to the study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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King Saud Medical City
Riyadh, Saudi Arabia
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Other studies related to the condition(s) this trial covers.
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- Can a simple questionnaire capture the true toll of metabolic surgery?