Pesticide exposure may fuel prostate cancer in martinique men
NCT ID NCT06773806
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether exposure to chlordecone, a pesticide banned in 1993 but still present in the environment, is linked to prostate cancer in men from Martinique. Researchers will compare 3600 men with and without prostate cancer, measuring chlordecone levels in blood and through questionnaires. The goal is to understand if this chemical increases cancer risk, especially in Afro-Caribbean populations.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 3,600 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Apr 2031
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Study participants will be selected from the Martinican male population under the age of 80.
- Ages
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18 to 75 years
- Sex
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Male participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
INCLUSION CRITERIA To take part in this research, participants must meet the following criteria: Patients/cases : * All men newly diagnosed with Prostate Cancer in Martinique during a three-year given period in all public and private services caring for patients with Prostate Cancer, identified via multidisciplinary consultation meetings. * Male adults under 75 years of age * Resident in Martinique for at least 6 months * Histologically confirmed (inclusion possible as soon as the result is known by the urologist) * Affiliated to a social security scheme or equivalent * Have signed a free and informed consent form Biopsy-negative" controls (Group 1 controls): * All men with a negative prostate biopsy following elevated Prostate Specific Antigen (PSA) assay (\> 2.5 ng/ml) within a 3-year period in all public and private services in Martinique identified via urologists or pathologists. * Male adults under 75 years of age * Resident in Martinique for at least 6 months * Frequency matched on age (+/- 5 years) to patients * Affiliated to a social security scheme or equivalent * Signed free and informed consent PSA-negative" controls (Group 2 controls): * All men with a PSA ⩽ 2.5 ng/ml within a 3-year period and less than 3 months identified via a survey institute * Male adults under 75 years of age * Resident in Martinique for at least 6 months * Frequency matched on age (+/- 5 years) against patients * Frequency matched on socio-professional category against men of the same age in Martinique (INSEE data) NON INCLUSION CRITERIA To take part in this research, participants must not meet the following criteria: * Be subject to a legal protection measure (safeguard of justice, curatorship or guardianship). * Inability to consent because does not speak French or Creole.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The private clinic "Clinique Saint-Paul"
NOT_YET_RECRUITINGFort-de-France, 97200, Martinique
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University Hospital of Martinique (CHUM)
RECRUITINGFort-de-France, 97261, Martinique
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A scanner in the operating room could show surgeons exactly where prostate cancer remains
- New PET tracer aims to light up hidden cancer targets
- Can daily adaptive radiotherapy spare healthy tissue in prostate cancer?
- Can a radioactive tracer and MRI reveal prostate Cancer's true extent?
- Five-Fraction radiation plus hormone therapy tested against High-Risk prostate cancer
- Can a 10-Hour eating window fight cancer fatigue?