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New gel may keep your jawbone strong after tooth loss

NCT ID NCT07571863

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a gel made from chitosan (a natural substance) can better preserve the jawbone after a tooth is pulled, compared to letting the socket heal on its own. Twenty-six adults with at least one hopeless tooth in the back of the jaw participated. Researchers used CT scans to measure bone width changes over six months.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

26 people

The number who actually took part.

Started

Dec 2024

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient having at least one hopeless tooth in posterior maxillary and mandibular area * 18 years old or older. * Motivated patients agree to sign the written informed consent and complete the follow up period * Medically fit patients. * No acute infections, pus formation, socket and bony discharges. * Compliant the patient to ensure the follow up Exclusion Criteria: * Heavy smokers (more than 10 cigarettes per day or an electronic cigarette dose of \>6 mg/ml of nicotine). * Pregnant females. * Presence of active infection or severe inflammation in the intervention zone. * Relevant medical history that contraindicates implant surgery. * Immunosuppression (eg. Hiv, solid-organ transplants). * Head and neck-irradiated patients in the past 5 years. * Regular intake of bisphosphonates, anticoagulants, or anti-inflammatories. * Chronic drug abuse or alcoholic habits. * Patients with poor oral hygiene (full-mouth plaque score and full-mouth bleeding score \>15%) and lack of motivation. * Uncontrolled diabetes (reported levels of glycated haemoglobin exceeding 7%). * Active periodontal disease. * Patients with significant comorbidity such as recent heart attack or coagulation disorder. * Patients with a history of allergies. * Mentally and physically handicapped patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculaty of Dentistry Cairo University, Cairo, Cairo 35855

    Cairo, Egypt

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