New gel may keep your jawbone strong after tooth loss
NCT ID NCT07571863
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a gel made from chitosan (a natural substance) can better preserve the jawbone after a tooth is pulled, compared to letting the socket heal on its own. Twenty-six adults with at least one hopeless tooth in the back of the jaw participated. Researchers used CT scans to measure bone width changes over six months.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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26 people
The number who actually took part.
- Started
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Dec 2024
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient having at least one hopeless tooth in posterior maxillary and mandibular area * 18 years old or older. * Motivated patients agree to sign the written informed consent and complete the follow up period * Medically fit patients. * No acute infections, pus formation, socket and bony discharges. * Compliant the patient to ensure the follow up Exclusion Criteria: * Heavy smokers (more than 10 cigarettes per day or an electronic cigarette dose of \>6 mg/ml of nicotine). * Pregnant females. * Presence of active infection or severe inflammation in the intervention zone. * Relevant medical history that contraindicates implant surgery. * Immunosuppression (eg. Hiv, solid-organ transplants). * Head and neck-irradiated patients in the past 5 years. * Regular intake of bisphosphonates, anticoagulants, or anti-inflammatories. * Chronic drug abuse or alcoholic habits. * Patients with poor oral hygiene (full-mouth plaque score and full-mouth bleeding score \>15%) and lack of motivation. * Uncontrolled diabetes (reported levels of glycated haemoglobin exceeding 7%). * Active periodontal disease. * Patients with significant comorbidity such as recent heart attack or coagulation disorder. * Patients with a history of allergies. * Mentally and physically handicapped patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculaty of Dentistry Cairo University, Cairo, Cairo 35855
Cairo, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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