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New hope for kids with leukemia: smarter chemo dosing could boost cures

NCT ID NCT03020030

First seen Jan 27, 2026 · Last updated Jun 18, 2026 · Updated 24 times

Summary

This study tests a new way to treat children and teens with acute lymphoblastic leukemia (ALL), the most common childhood cancer. Researchers are using updated risk factors to decide how strong chemotherapy should be and adjusting doses of a key drug based on blood levels. The goal is to improve cure rates while reducing side effects. About 560 participants will be followed for several years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Boston Children's Hospital

    Boston, Massachusetts, 02115, United States

  • Centre Hospitalier U. de Quebec

    Québec, Quebec, Canada

  • Columbia University Medical Center, Morgan Stanley Children's Hospital of New York-Presbyterian

    New York, New York, 10032, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Hasbro Children's Hospital / Rhode Island Hospital

    Providence, Rhode Island, 02903, United States

  • Hospital Sainte Justine, University of Montreal

    Montreal, Quebec, Canada

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08903, United States

Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia childhood acute lymphoblastic leukemia Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.