Chemo ear damage worse for poorer patients, study warns
NCT ID NCT07553481
First seen Jun 27, 2026 · Last updated Sep 11, 2026 · Updated 2 times
Summary
This study looks at how platinum-based chemotherapy can cause permanent hearing loss in cancer patients, and whether people from poorer backgrounds are more affected. Researchers will test hearing and thinking skills in 172 patients from North West England before and after treatment. The goal is to find health gaps and guide better hearing care for cancer survivors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 172 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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Sep 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Cancer patients who will be treated with platinum-based chemotherapy drugs within the North West of England. Participants will be recruited from NHS Hospital Trusts from across the North West of England.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients receiving platinum-based chemotherapy drugs * Living and treated within North West England * Able to complete an online hearing and cognitive test * Fluent in English Exclusion Criteria: * Following cancer types: brain tumour/metastasis, head + neck, skin cancers around the ear, and adenoid cystic carcinoma of the auditory cortex * World Health Organisation performance status score of 3 or more * Stage 4 cancer * History of childhood deafness * Current or recent ear infections * Cochlear implant user * Known neurological impairment (e.g., stroke, traumatic brain injury, dementia) * Patients who look capacity to consent or complete study tasks
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Lancaster University
RECRUITINGLancaster, Lancashire, LA1 4YW, United Kingdom
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