Wine waste chocolate may help hearts, tiny study hints

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Screening or Visit 1 Reactive Hyperemia Index (RHI; EndoPAT 2000) \< 2.0 * Subject is willing and able to comply with the study protocols. * Subject is willing to participate in all study procedures * BMI 25.0 - 35 kg/m2 Exclusion Criteria: * BMI ≥ 35 kg/m2 * Indivduals that weight less than a 110 lbs * Donation of blood within the previous 30 days * Visit 1 Reactive Hyperemia Index (RHI; EndoPAT 2000) ≥ 2.0 * 1 ug/ml and 3 ug/ml collagen screening maximal platelet aggregatory response of \< 65%. * Platelet counts \< 150,000 / ul * Anemia, which includes self report, or a screening hemoglobin and hematocrit that is less than the normal reference range or as diagnosed by study physician upon review of complete blood cell count reports. * Dislike or allergy for nuts, cocoa or grape products * Self-reported use of daily anticoagulation agents including aspirin, NSAIDs * Vegan, Vegetarians, food faddists or those consuming a non-traditional diet * Fruit consumption ≥ 3 cups/day * Vegetable consumption ≥ 4 cups/day * Nut intake ≥ 2 servings/ week * Coffee/tea ≥ 3 cups/day * Dark chocolate ≥ 3 oz/day * Self-reported restriction of physical activity due to a chronic health condition * Self-reported chronic/routine high intensity exercise * Self-reported diabetes * Blood pressure ≥ 140/90 mm Hg * Self-reported renal or liver disease * Self-reported heart disease, which includes cardiovascular events and stroke * Peripheral artery disease, Raynaud's syndrome * Inability to properly place or wear the PAT probes or abnormal measurements on pre- screening PAT * Self-reported cancer within past 5 years * Self-reported malabsorption * Currently taking prescription drugs or supplements. * Supplement use or unwillingness to stop any supplement use, including herbal, plant or botanical, fish oil, oil supplements a month prior to study enrollment. * Indications of substance or alcohol abuse within the last 3 years * smoking, vaping, cannabis use * Current enrollee in a clinical research study.