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Shoulder pain study: why some patients may not respond to steroid shots

NCT ID NCT06404125

Knowledge-focused Sponsor: Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at 44 people with shoulder pain from rotator cuff problems to see if their level of central sensitization (a heightened pain response in the nervous system) affected how well a steroid injection worked. Researchers measured pain sensitivity before the injection and then checked outcomes like shoulder movement and grip strength. The goal was to understand why some patients don't respond to this common treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
corticosteroid injection
What this could lead to
If it works, this could help doctors predict which patients with shoulder pain will benefit from steroid injections, leading to more personalized treatment.
What could go wrong
This is a small, completed observational study, not a treatment trial. It only looks at a possible link, so it cannot prove that changing treatment based on central sensitization improves outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

44 people

The number who actually took part.

Started

Mar 2023

Finished

Jul 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Rotator cuff lesion patients aged between 18-65 years old, who have received medical treatment as part of routine practice and have not had an adequate response will be evaluated before and after injection visiting our physical medicine and rehabilitation outpatient clinic between March 2023 and June 2024.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Clinically and radiographically confirmed rotator cuff pathology * Being between the ages of 18-65 * Non-response to medical treatment * Being literate * To agree to participate in the study Exclusion Criteria: * History of shoulder trauma and previous shoulder surgery * Injection in the shoulder area in the last 3 months * History of active cancer, systemic inflammatory disease and infection * Pregnancy * Under 18 and over 65 years of age * Illiteracy * Refusal to participate in the study

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome rotator cuff syndrome shoulder impingement syndrome Shoulder Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic pain Rotator cuff lesion Shoulder pain Subacromial impingement syndrome

Contacts and locations

Locations

  • Sultan 2. Abdulhamid Han Training and Research Hospital

    Istanbul, Üsküdar, 34674, Turkey (Türkiye)

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