Drug combo shows promise for Tough-to-Treat ovarian and breast cancers
NCT ID NCT01116648
First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 17 times
Summary
This study tested whether combining two drugs—cediranib (which cuts off a tumor's blood supply) and olaparib (which blocks cancer cell repair)—works better than olaparib alone for people with certain ovarian, fallopian tube, peritoneal, or triple-negative breast cancers that have come back. About 155 adults took part. The goal was to find the safest dose and see if the combo delays cancer growth longer than the single drug.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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Cedars Sinai Medical Center
Los Angeles, California, 90048, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Fort Wayne Medical Oncology and Hematology Inc - Jefferson Boulevard
Fort Wayne, Indiana, 46804, United States
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Fort Wayne Medical Oncology and Hematology Inc-Parkview
Fort Wayne, Indiana, 46845, United States
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Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland, 21287, United States
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Massachusetts General Hospital
Charlestown, Massachusetts, 02129, United States
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Massachusetts General Hospital Cancer Center
Boston, Massachusetts, 02114, United States
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National Cancer Institute
Rockville, Maryland, 20850, United States
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
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Newton-Wellesley Hospital
Newton, Massachusetts, 02462, United States
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NorthShore University HealthSystem-Evanston Hospital
Evanston, Illinois, 60201, United States
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University of Chicago Comprehensive Cancer Center
Chicago, Illinois, 60637, United States
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University of Michigan Rogel Cancer Center
Ann Arbor, Michigan, 48109, United States
Conditions
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