New cancer drug copycat tested in healthy people
NCT ID NCT03881787
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tested a new drug called CDP1, which is a close copy of the cancer drug Erbitux, in 84 healthy male volunteers. The goal was to see how the body handles CDP1, whether it causes side effects, and if it triggers an immune response. The results will help decide if CDP1 can move into larger studies in cancer patients.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- anti-EGFR monoclonal antibody (CDP1)
- What this could lead to
- If successful, this could support CDP1 as a more affordable alternative to Erbitux for treating certain cancers.
- What could go wrong
- This is an early-phase trial in healthy people, not patients. It only checks safety and drug levels, not whether it works against cancer. The drug may still fail in later trials.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 1
The first testing in people. Mainly checks safety and dose, usually in a small group.
- Participants
-
84 people
The number who actually took part.
- Started
-
Apr 2017
- Finished
-
Aug 2019
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 45 years
- Sex
-
Male participants only
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Healthy adult volunteers participate in clinical trials voluntarily and sign informed consent. 2. Age 18 \~ 45 (inclusive) years , male. 3. The body weight is not less than 50 kg, and the body mass index is between 18.5 and 26 (including both ends). 4. Good health, no heart, liver, kidney or other acute or chronic digestive tract diseases, respiratory diseases, blood, endocrine, nervous, mental and other systemic diseases. 5. Physical examination, vital signs, blood routine, urine routine, blood biochemistry, electrocardiogram and chest X-ray examination are all normal, or the abnormal results of the examination are not clinically meaningful by the investigator. 6. Agree to avoid spouse pregnancy during the trial period and within 6 months after the end of the administration. Exclusion Criteria: 1. Allergic constitution, those who are allergic to the test drug ingredients or have a history of allergies to any drug or food or a history of pollen allergy; those with abnormal serum immunoglobulin E (IgE) (more than 3 times higher than the upper limit of normal). 2. Anti-drug antibody (ADA) positive. 3. Infections currently in need of clinical treatment. 4. HBsAg, HBeAg, HCV-Ab, HIV-Ab or TP-Ab positive. 5. Upon inquiry, there is a clear current medical history of the central nervous system, cardiovascular system, kidney, liver, digestive system, respiratory system, metabolic system or other significant diseases. 6. Upon inquiry, a person with a history of mental illness. 7. Upon inquiry, there is a history of cancer and it is judged by the investigator that it is not suitable for participation. 8. According to the investigator's judgment, the investigator believes that it is not suitable for the participants in this clinical trial for various reasons.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Healthy volunteers are added.
Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Shanghai Public Health Clinical Center
Shanghai, Shanghai Municipality, China
-
West China Hospital
Chengdu, Sichuang, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Scientists probe the nerve highways behind strength gains
- New syphilis test kits put to the test with donated blood
- Can a copy of a blockbuster arthritis drug match the original? scientists test it in healthy people
- Novo nordisk tests Brand-New molecule in humans for the first time
- New sedative candidate goes Head-to-Head with propofol in early human test
- Can a Room-Temperature dairy drink build muscle?