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New cancer drug copycat tested in healthy people

NCT ID NCT03881787

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tested a new drug called CDP1, which is a close copy of the cancer drug Erbitux, in 84 healthy male volunteers. The goal was to see how the body handles CDP1, whether it causes side effects, and if it triggers an immune response. The results will help decide if CDP1 can move into larger studies in cancer patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
anti-EGFR monoclonal antibody (CDP1)
What this could lead to
If successful, this could support CDP1 as a more affordable alternative to Erbitux for treating certain cancers.
What could go wrong
This is an early-phase trial in healthy people, not patients. It only checks safety and drug levels, not whether it works against cancer. The drug may still fail in later trials.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1

The first testing in people. Mainly checks safety and dose, usually in a small group.

Participants

84 people

The number who actually took part.

Started

Apr 2017

Finished

Aug 2019

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Healthy adult volunteers participate in clinical trials voluntarily and sign informed consent. 2. Age 18 \~ 45 (inclusive) years , male. 3. The body weight is not less than 50 kg, and the body mass index is between 18.5 and 26 (including both ends). 4. Good health, no heart, liver, kidney or other acute or chronic digestive tract diseases, respiratory diseases, blood, endocrine, nervous, mental and other systemic diseases. 5. Physical examination, vital signs, blood routine, urine routine, blood biochemistry, electrocardiogram and chest X-ray examination are all normal, or the abnormal results of the examination are not clinically meaningful by the investigator. 6. Agree to avoid spouse pregnancy during the trial period and within 6 months after the end of the administration. Exclusion Criteria: 1. Allergic constitution, those who are allergic to the test drug ingredients or have a history of allergies to any drug or food or a history of pollen allergy; those with abnormal serum immunoglobulin E (IgE) (more than 3 times higher than the upper limit of normal). 2. Anti-drug antibody (ADA) positive. 3. Infections currently in need of clinical treatment. 4. HBsAg, HBeAg, HCV-Ab, HIV-Ab or TP-Ab positive. 5. Upon inquiry, there is a clear current medical history of the central nervous system, cardiovascular system, kidney, liver, digestive system, respiratory system, metabolic system or other significant diseases. 6. Upon inquiry, a person with a history of mental illness. 7. Upon inquiry, there is a history of cancer and it is judged by the investigator that it is not suitable for participation. 8. According to the investigator's judgment, the investigator believes that it is not suitable for the participants in this clinical trial for various reasons.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Shanghai Public Health Clinical Center

    Shanghai, Shanghai Municipality, China

  • West China Hospital

    Chengdu, Sichuang, China

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