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New drug targets DNA in Hard-to-Treat cancers

NCT ID NCT05691517

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 33 times

Summary

This early-stage trial is testing a drug called CBX-12 in people with advanced solid tumors that have spread and stopped responding to at least one prior treatment. The drug works by entering cancer cells and damaging their DNA, which can kill the cells. The study aims to see how well CBX-12 works and how it affects the body, with about 35 participants.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Cancer Institute Developmental Therapeutics Clinic

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.