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Back pain breakthrough? study seeks clues to who benefits from nerve scar treatment

NCT ID NCT07487935

Knowledge-focused Sponsor: Mersin University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study reviews medical records of 40 adults with chronic leg pain from back problems who had a procedure called caudal epidural adhesiolysis. The procedure uses a thin tube to break up scar tissue around spinal nerves. Researchers want to find out which patient traits or procedure details lead to better pain relief. The goal is to help doctors choose the right patients for this treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
caudal epidural adhesiolysis (a minimally invasive procedure to break up scar tissue around spinal nerves)
What this could lead to
If successful, this study could help doctors identify which patients with chronic back and leg pain are most likely to benefit from this procedure, leading to better treatment decisions.
What could go wrong
This is a small, single-center retrospective study (only 40 patients) that looks back at medical records, so it cannot prove cause and effect. Results may not apply to other clinics or patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

40 people

The number who actually took part.

Started

Jan 2023

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of adult patients with chronic lumbar radicular pain or pain related to epidural adhesions who underwent caudal epidural adhesiolysis at the Mersin University Faculty of Medicine, Algology Clinic between March 1, 2023, and January 1, 2026. Only patients who met the predefined inclusion and exclusion criteria and had available pre-procedural, procedural, and post-procedural follow-up data, including Numeric Rating Scale (NRS) and Oswestry Disability Index (ODI) scores, were included in the analysis.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older * Underwent caudal epidural adhesiolysis at the Mersin University Faculty of Medicine, Algology Clinic between March 1, 2023, and January 1, 2026 * Evaluated with a diagnosis of chronic lumbar radicular pain or pain related to epidural adhesions * Availability of pre-procedural clinical data in the medical records * Availability of procedural technical records in the medical file, including at minimum the procedure date, the level to which the catheter was advanced, and the medications administered and/or procedural details * Availability of post-procedural follow-up data including Numeric Rating Scale (NRS) and Oswestry Disability Index (ODI) scores Exclusion Criteria: * Patients younger than 18 years * Patients who underwent caudal epidural adhesiolysis outside the period from March 1, 2023, to January 1, 2026, at the Mersin University Faculty of Medicine, Algology Clinic * Patients without a diagnosis of chronic lumbar radicular pain or pain related to epidural adhesions * Missing essential pre-procedural clinical data in the medical records * Insufficient procedural technical documentation in the medical file * Absence of post-procedural clinical follow-up data * Missing Numeric Rating Scale (NRS) and Oswestry Disability Index (ODI) scores in the follow-up records

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Conditions

The condition(s) this trial relates to.

lumbar disk degenerative disorder lumbar disk disease radiculopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Adhesiolysis Disc disease lumbar Radicular pain

Contacts and locations

Locations

  • Mersin University Faculty of Medicine, Department of Pain Medicine

    Mersin, Ciftlikkoy, 33110, Turkey (Türkiye)

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