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New study reveals key infection risks for intestinal failure patients

NCT ID NCT07172711

Knowledge-focused Sponsor: Jinling Hospital, China Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 2 times

Summary

This study looked at 321 hospitalized patients with intestinal failure to find out what makes them more likely to get a bloodstream infection from their catheter. Researchers identified specific risk factors for different types of intestinal failure. The goal is to help doctors prevent these infections and improve patient outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could lead to better prevention strategies for catheter infections in intestinal failure patients, reducing hospital stays and costs.
What could go wrong
This is a retrospective study, so it can show associations but not prove cause and effect. The findings may not apply to all patient groups or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

321 people

The number who actually took part.

Started

Jan 2025

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This single-center retrospective study enrolled 321 patients with intestinal failure admitted between 2021 and 2024. All included patients met the ESPEN 2023 diagnostic criteria for intestinal failure, defined as reduced intestinal function below the minimum necessary for absorption of macronutrients and/or water-electrolytes, thus requiring intravenous supplementation (IVS) to maintain health and/or growth. Patients were excluded if they met any of the following criteria: Catheter indwelling duration \<48 hours; Implanted catheter before admission; Complex components in PN difficult to quantify; Positive blood cultures with unclear CRBSI diagnosis; Alternative infection sources identified.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients meeting the ESPEN 2023 diagnostic criteria for intestinal failure. Exclusion Criteria: * Catheter indwelling duration \<48 hours; Implanted catheter before admission; Complex components in PN difficult to quantify; Positive blood cultures with unclear CRBSI diagnosis; Alternative infection sources identified.

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Conditions

The condition(s) this trial relates to.

chronic intestinal failure Intestinal Failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Catheter-related bloodstream infection Intestinal failure

Contacts and locations

Locations

  • Jinling Hospital

    Nanjing, Jiangsu, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.