New study tracks clues to predict transplant complication
NCT ID NCT04188912
First seen Oct 31, 2025 · Last updated Jun 23, 2026 · Updated 38 times
Summary
This study followed 267 adults who had stem cell transplants to understand why some develop chronic graft-versus-host disease (GVHD), a common complication. Researchers collected blood, saliva, tears, and tissue samples, along with eye scans and breathing tests, to find early signs of the condition. The goal is to help doctors predict and detect chronic GVHD sooner.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Fred Hutch/University of Washington Cancer Consortium
Seattle, Washington, 98109, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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National Cancer Institute
Bethesda, Maryland, 20892, United States
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Roswell Park
Buffalo, New York, 14263, United States
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University of Florida
Gainesville, Florida, 32610, United States
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Vanderbilt
Nashville, Tennessee, 37212, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help doctors predict and catch chronic GVHD earlier after stem cell transplants.
What could go wrong
This is an observational study, not testing a treatment. It may not lead to direct improvements for patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.