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Eye surgery showdown: which technique spares more corneal cells?

NCT ID NCT02535819

Knowledge-focused Sponsor: Centre Hospitalier Régional Metz-Thionville Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

Cataracts cloud the eye's lens and can lead to blindness if untreated. This study compared two common surgical techniques—Divide-and-Conquer and Subluxation—to see which causes less damage to the cornea's inner cell layer. 294 adults having cataract surgery took part, and researchers measured cell loss before and after the operation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If one technique clearly causes less cell loss, surgeons may adopt it to better protect patients' corneas during cataract surgery.
What could go wrong
This is an observational comparison, not a test of a new treatment. Results may not change practice if differences are small or not clinically meaningful.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

294 people

The number who actually took part.

Started

Jun 2015

Finished

May 2018

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female aged ≥ 18 years * Patients undergoing cataract surgery * Visual acuity Monoyer scale \<6/10e (\< +0.2 logMar) * Nuclear, cortical and posterior subcapsular cataract with normal density to severe in the LOCSIII classification Exclusion Criteria: * insulin-dependent diabetes and /or diabetic retinopathy * corneal disease: keratitis, dystrophy, corneal degeneration * Any disease of intraocular pressure * Any disease of the anterior segment * Low preoperative endothelial cell density \< 1500 c/mm² * Combined surgery (cataract + corneal transplant, cataract + glaucoma surgery, cataract +vitrectomy ...) * Risk factors for surgical per-operative complication * Pregnancy, lactation * Ward of court * Patient not covered by the Social Security scheme

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Conditions

The condition(s) this trial relates to.

cataract

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cataracts

Contacts and locations

Locations

  • Chr Metz Thionville

    Metz, 57085, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.