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Scientists hunt for better ways to diagnose and treat rare bone tumors

NCT ID NCT07315542

Knowledge-focused Sponsor: St. Anne's University Hospital Brno, Czech Republic Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at 300 people with cartilage tumors, including both benign types and the cancer chondrosarcoma. Researchers are studying genetic changes and molecules called miRNAs to better tell these tumors apart and predict outcomes. The goal is to improve diagnosis and find new treatment targets for hard-to-treat cases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 300 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2025

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of patients with cartilaginous (chondroid) tumours treated at the First Department of Orthopaedic Surgery, St. Anne's University Hospital Brno, a national referral centre for bone tumours.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Histologically confirmed cartilaginous (chondroid) tumour * Diagnosis includes one of the following entities (as available and eligible): * Enchondroma * Atypical cartilaginous tumour / Grade 1 chondrosarcoma (ACT/G1) * Conventional chondrosarcoma (Grade 2-3) * Dedifferentiated chondrosarcoma * Other rare chondrosarcoma variants (e.g., mesenchymal, clear-cell), if present in the cohort * Patients treated and/or followed at the First Department of Orthopaedic Surgery, St. Anne's University Hospital Brno Exclusion Criteria * Insufficient, degraded, or otherwise unusable tissue samples

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Conditions

The condition(s) this trial relates to.

chondrogenic neoplasm chondroma chondrosarcoma clear cell chondrosarcoma dedifferentiated chondrosarcoma mesenchymal chondrosarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cartilage tumours Chondrosarcomas

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • First Department of Orthopaedic Surgery, St. Anne's University Hospital and Faculty of Medicine, Masaryk University, Brno, Czechia

    RECRUITING

    Brno, South Moravian, 60200, Czechia

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