Simple hand exercises may ease carpal tunnel pain without surgery
NCT ID NCT07653789
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether nerve gliding exercises, tendon gliding exercises, or a combination of both can reduce pain and improve hand function in people with mild to moderate carpal tunnel syndrome. Participants will be randomly assigned to one of three groups and followed for changes in pain and symptoms. The goal is to find a non-surgical, low-cost approach to managing this common condition.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- neuromobilization techniques and tendon gliding exercises
- What this could lead to
- If effective, these simple exercises could offer a drug-free way to reduce pain and improve hand function in people with mild to moderate carpal tunnel syndrome.
- What could go wrong
- This is a small, early-stage trial with only 52 participants, so results may not apply to everyone. The exercises may not work for severe cases or those with other conditions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 52 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * • Symptoms of CTS (pain, paresthesia in the area of hand innervated by the median nerve) * First and Second Trimester Pregnant women. * Mild to Moderate CTS patients. * Individuals experiencing wrist pain for a duration of at least 6-8 weeks without a history of trauma or specific diagnosis (e.g., fracture, arthritis). * Pain rated between 3 and 5 on (NPRS). * Present neurological disorders (e.g., carpal tunnel syndrome, cervical radiculopathy). * No prior physical therapy treatment for wrist pain in the last 3-6 months Exclusion Criteria: * • History of traumatic injury, fracture, or surgery to the wrist or hand. * Diagnosis of systemic diseases affecting the wrist (e.g., rheumatoid arthritis, gout, or diabetes-related neuropathy). * Any skin condition or infection around the wrist that would contraindicate physical therapy. * Third Trimester Pregnant women * Individuals with serious cardiovascular or metabolic disorders. * patients currently undergoing other treatments specifically targeting CTS (e.g., steroid injections)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Dr. Akbar Niazi teaching Hospital
RECRUITINGIslamabad, ICT, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Three shots, one wrist: which injection best eases carpal tunnel?
- Scalpel vs sound waves: two carpal tunnel surgeries go head to head
- Can carpal tunnel surgery restore more than hand function?
- Does nerve healing keep pace with hand recovery after carpal tunnel surgery?
- Retraining the brain to ease carpal tunnel pain: a new approach put to the test
- Can a Two-Session acupuncture treatment match ten sessions for carpal tunnel?