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No tourniquet, less pain? study tests new approach for carpal tunnel release

NCT ID NCT07617064

Symptom relief Sponsor: Misr University for Science and Technology Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two numbing methods for carpal tunnel surgery in 100 adults. One method uses lidocaine with epinephrine and no tourniquet (WALANT), while the other uses lidocaine alone with a tourniquet. The main goal was to see which method causes less pain during the operation. Patients rated their pain on a scale from 0 to 10.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
lidocaine with epinephrine (WALANT technique) vs lidocaine alone with tourniquet
What this could lead to
If WALANT proves less painful, it could become the preferred method for carpal tunnel surgery, reducing patient discomfort and simplifying the procedure.
What could go wrong
This is a small, completed trial (100 participants) comparing two established techniques. Results may not apply to all patients or settings, and individual pain responses vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

100 people

The number who actually took part.

Started

Sep 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults (≥18 years) with clinically and electrophysiologically confirmed carpal tunnel syndrome. Candidate for surgical treatment with open carpal tunnel decompression. American Society of Anesthesiologists (ASA) physical status I or II. Able and willing to provide written informed consent. Exclusion Criteria: * Surgery-related anxiety requiring sedation or general anesthesia. Known contraindication or allergy to lidocaine or epinephrine. Active local or systemic infection at or near the surgical site. ASA physical status III or higher. Pregnancy or breastfeeding. Any condition preventing reliable pain scoring or follow-up according to investigator judgment.

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Conditions

The condition(s) this trial relates to.

carpal tunnel syndrome Patient Satisfaction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Carpal tunnel syndrome

Contacts and locations

Locations

  • Al-Azhar University Hospital (Neurosurgery Department)

    Cairo, Egypt

  • Misr University for Science and Technology Hospital (Orthopedic Surgery Department)

    Giza, Egypt

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