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Sugar water injection may rival steroids for carpal tunnel pain

NCT ID NCT06360510

Symptom relief Sponsor: Gaziler Physical Medicine and Rehabilitation Education and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study tested whether an injection of 5% dextrose (a sugar solution) works as well as a steroid (betamethasone) to relieve pain and symptoms in people with mild-to-moderate carpal tunnel syndrome. Thirty participants received one of the two ultrasound-guided injections. The goal was to see if the safer, non-steroid option could provide similar relief.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
5% dextrose injection and betamethasone injection
What this could lead to
If dextrose works as well as betamethasone, it could offer a safer, steroid-free option for managing carpal tunnel pain.
What could go wrong
This is a small, completed trial with only 30 participants, so results may not apply widely. Dextrose may prove less effective than the standard steroid treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

30 people

The number who actually took part.

Started

May 2023

Finished

May 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

patients that have carpal tunnel syndrome

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Paresthesia and pain symptoms in the region corresponding to the distribution of the median nerve * Detection of mild or moderate CTS by electromyography * One or both of the Phalen test and/or Tinel sign are positive on physical examination * Symptoms have persisted for at least 3 months Exclusion Criteria: * Those diagnosed with polyneuropathy, plexopathy, radiculopathy, thoracic outlet syndrome * Having had surgery or any injection for carpal tunnel syndrome within the last year * History of wrist fracture * Those with rheumatoid arthritis, uncontrolled diabetes, gout, chronic renal failure, malignancy, active systemic infection * Those with cognitive impairment * Coagulopathy or bleeding tendency * Pregnancy

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Conditions

The condition(s) this trial relates to.

carpal tunnel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Carpal tunnel syndrome

Contacts and locations

Locations

  • Ankara Gaziler Physical Medicine and Rehabilitation Education and Research Hospital

    Ankara, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.