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Eye-Opening study: could a simple supplement protect your retina?

NCT ID NCT07314411

Knowledge-focused Sponsor: Pacific University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether taking a daily carotenoid supplement for 3 months can improve retinal health in healthy adults aged 18-75. Researchers will measure changes in macular pigment, retinal thickness, blood flow, and vision, as well as cognitive function. Participants are randomly assigned to receive either the supplement or a placebo. The goal is to understand if these nutrients can help protect the retina and reduce waste buildup.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
carotenoid supplement (dietary supplement)
What this could lead to
If it works, this could show that a simple daily supplement helps protect the retina and may reduce the risk of age-related vision problems.
What could go wrong
This is a small, early-stage trial in healthy people, so results may not apply to those with eye disease. The supplement may show no benefit over placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2025

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18-75 years * Monocular best corrected visual acuity (BCVA) of 20/20 or better * Eye pressure between 8 and 22 mm of Hg (will be screened in study if needed) * Ability to provide informed consent * Access to the Internet Exclusion Criteria: * History of or currently active eye diseases or systemic disease * History of refractive surgery or ocular surgery * Currently pregnant, nursing or planning to become pregnant during the study period * Known allergy to any study active or inactive ingredient * Current supplementation with any components of MacuHealth or placebo softgel capsules * Drugs that may interact with absorption of fat-soluble vitamins/carotenoids especially orlistat and bile acid sequestrants (i.e., colestyramine, fat-free substitutes such as Olestra, beta-carotene, and vitamin E), or antidiabetic drugs

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Pacific University

    RECRUITING

    Forest Grove, Oregon, 97116, United States

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