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Massive shanghai study aims to uncover hidden links between heart, kidney, and metabolic diseases

NCT ID NCT07043166

Knowledge-focused Sponsor: Shanghai Changzheng Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study follows 4,094 adults in Shanghai who were part of an earlier health survey. Researchers will track them for up to 10 years to see how heart disease, kidney problems, and metabolic conditions like diabetes and obesity develop and interact. The goal is to better understand these connections and improve future prevention and care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could reveal how heart, kidney, and metabolic diseases are connected, helping doctors predict and prevent them earlier.
What could go wrong
This is an observational study, not a treatment trial. It only tracks health over time, so it won't directly cure or treat any disease. Results may take years to apply.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 4,094 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2025

Expected to finish

Dec 2035

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

A total of 4,094 residents were drawn from 10 communities in Shanghai, with baseline multidimensional data collected."

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. The 4,094 residents of Shanghai communities who have been enrolled in the STONE cohort. 2. Individuals who completed the baseline questionnaire survey, physical examination, and related clinical tests between 2016 and 2017, with complete data records. 3. Willingness to participate in this follow-up study and provision of informed consent. Exclusion Criteria: 1. Participants who have moved away from their original community and have been living elsewhere for more than two years. 2. Participants whose contact information has changed or become invalid, resulting in loss of contact (those who remain uncontactable after three attempts to reach out).

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Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome Bone Diseases, Metabolic cardiovascular disorder cardiovascular-kidney-metabolic syndrome chronic kidney disease chronic renal failure syndrome diabetes mellitus Dyslipidemias hypertensive disorder inherited lipid metabolism disorder metabolic bone disorder metabolic disease metabolic syndrome X Obesity obesity disorder Overweight thyroid gland disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bone metabolism disorder Cardiovascular diseases (CVD) Cardiovascular-kidney-metabolic syndrome Chronic kidney disease (CKD) Diabetes Dyslipidemia Hypertension Metabolic syndrome Obesity and overweight Thyroid diseases

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Shanghai Changzheng Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200003, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.