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Childhood stress may harm your heart later in life

NCT ID NCT06557707

Knowledge-focused Sponsor: Virginia Commonwealth University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Sep 15, 2026 · Updated 6 times

Summary

This study looks at how stress during childhood can impact heart and blood vessel health later on. Researchers will measure heart function, blood vessel flexibility, and lung function in 120 participants aged 9-30. The goal is to understand early signs of disease so that future prevention can be improved.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could help identify early signs of heart disease linked to childhood stress, leading to better prevention strategies.
What could go wrong
This is an observational study, not a treatment trial. It may not directly change medical practice, and results might not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

71 people

The number who actually took part.

Started

Jan 2022

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Children and young individuals who have been exposed to adversity during childhood

Ages

9 to 30 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Cohort 1 * Men and pre-menopausal women * 18-30 years old Cohort 2 * males and females * 9-17 years old Exclusion Criteria: Cohort 1 * Evidence of cardiovascular, pulmonary, renal, hepatic or cerebral diseases * Evidence of pregnancy or currently nursing. * Having a history of chronic pain * Having a history of rheumatoid arthritis Cohort 2 * Evidence of cardiovascular, pulmonary, renal, hepatic or cerebral diseases * Evidence of pregnancy or currently nursing. * Having a history of chronic pain * Having a history of rheumatoid arthritis

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stress

Contacts and locations

Locations

  • Virginia Commonwealth University

    Richmond, Virginia, 23298, United States

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