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Massive heart database aims to unlock secrets of cardiovascular disease

NCT ID NCT00378924

Knowledge-focused Sponsor: Emory University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This study creates a large database of about 12,000 people with and without heart disease. Researchers collect medical information and blood samples to analyze factors that influence heart conditions like coronary artery disease, heart failure, and stroke. The goal is to better understand what causes these diseases and how to treat them more effectively.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this database could help doctors identify factors that cause or worsen heart disease and improve treatment strategies.
What could go wrong
This is an observational registry, not a treatment trial. It collects data but does not test any new drug or therapy, so direct patient benefits may take years.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 12,000 people

The number the study aims to enrol. It can still change while the study runs.

Start date

Dec 2003

Expected to finish

Apr 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

General population \& patients presenting to the hospital

Ages

20 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. All hospital and clinic participants aged 18 years and older 2. Participants with and without active or presumed cardiovascular disease including but not limited to: 1. Coronary Artery Disease 2. Heart Failure and Cardiomyopathies 3. Peripheral Vascular Disease 4. Valve disease 5. Adult Congenital Heart disease 6. Electrophysiological Disorders 3. Any individual aged 18 and above in satisfactory physical health and able to tolerate a blood draw or buccal swab. Exclusion Criteria: 1. Significant Documented Anemia (Hemoglobin \<8 g/dL) 2. Blood transfusions within past 3 weeks 3. Enrollment against doctor recommendation 4. Participant not able to provide consent including but not limited to: 1. Intubated and critically unwell participants 2. Dementia 3. Alzheimer's disease 4. Moderate to severe alcohol or drug abuse 5. Against religious beliefs (e.g. Jehovah's witness)

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiovascular disease

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Emory School Of Medicine

    RECRUITING

    Atlanta, Georgia, 30322, United States

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