New rehab program aims to protect cancer Survivors' hearts

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older, regardless of sex. * Histologically or cytologically confirmed solid tumor or hematologic malignancy. * Completed curative anti-cancer therapy, or receiving stable adjuvant, maintenance, or palliative anti-cancer therapy. * Meets at least one criterion for cancer therapy-related cardiac dysfunction (CTRCD) or high cardiovascular risk, including reduced LVEF after anti-cancer therapy, high-dose anthracycline exposure, chest radiotherapy with cardiovascular risk factors, heart failure after anti-cancer therapy, or elevated cardiac injury/heart failure biomarkers. * Estimated life expectancy of at least 24 months as assessed by the treating oncologist. * Able to complete baseline cardiopulmonary exercise testing and has no absolute contraindication to exercise training. * Able and willing to provide written informed consent and comply with study intervention and follow-up. Exclusion Criteria: * Active progressive malignancy requiring urgent anti-cancer therapy, or estimated life expectancy less than 24 months. * Severe structural heart disease, including severe valvular disease, congenital heart disease, end-stage heart failure, or waiting for heart transplantation or left ventricular assist device implantation. * Absolute contraindications to exercise training, including uncontrolled malignant arrhythmia, acute myocarditis or pericarditis, acute coronary syndrome within 2 weeks, severe anemia, severe thrombocytopenia or neutropenia, uncontrolled hypertension, active infection, or severe musculoskeletal disease preventing exercise training. * Participation in a structured cardiac rehabilitation program within the previous 12 months, or regular moderate-to-vigorous aerobic or resistance training for at least 3 months before enrollment. * Implanted ICD or CRT, except pacemakers with exercise mode. * Severe psychiatric disease or cognitive impairment preventing participation. * Concurrent participation in another interventional clinical trial, or planned participation in another interventional clinical trial during the study period. * Any other condition that, in the investigator's judgment, makes the participant unsuitable for the study.