700-Patient study aims to unlock secrets of CAR-T success and failure
NCT ID NCT07609485
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study collects blood and tumor samples from 700 adults receiving approved CAR-T therapy for blood cancers. Researchers will analyze these samples to identify biological markers that predict whether the therapy will work or if the cancer will return. The goal is to improve future CAR-T treatments by understanding why some patients respond well while others do not.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors predict which patients will benefit most from CAR-T therapy and why some patients relapse.
- What could go wrong
- This is an observational study, not a treatment trial. It will not directly improve outcomes for participants and may not lead to new biomarkers.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 700 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2021
- Expected to finish
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Feb 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Samples from eligible patients who receives commercially available CAR-T therapy will be collected and stored at regular intervals
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male or female aged ≥ 18 years and able to provide informed consent * Any indication, * Commercially available CART therapies, * Any conditioning. Exclusion Criteria: * Freedom privacy * Absence of medical coverage * Patients receiving CART or CAR-based cellular therapies which are not commercially available.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hop Claude Huriez Chu Lille
TERMINATEDLille, 59037, France
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chu de Lille
RECRUITINGLille, France
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